2025-11-182025-11-18https://repositorio.uandes.cl/handle/uandes/57648<p>The inflammatory response associated with extreme preterm birth plays a relevant role in the prognosis of the newborn. The immaturity of the immune system fails to modulate the pro-inflammatory and anti-inflammatory mechanisms, triggering secondary damage with short, medium and long term sequelae. Objective: to review the immunological mechanisms involved in the sustained perinatal inflammatory syndrome, presenting possible prevention and treatment targets.</p>info:eu-repo/semantics/openAccessExtreme PretermImmunological BasisInflammationSequelsSustained Perinatal Inflammatory SyndromeSÍNDROME INFLAMATORIO PERINATAL PERSISTENTE. IMPORTANTE FACTOR DE MORBIMORTALIDAD EN EL PREMATURO EXTREMOPARTE I: NOCIONES BÁSICAS DE INMUNOLOGÍA SUSTAINED PERINATAL INFLAMMATORY SYNDROME OF THE EXTREME PRETERM INFANT. IMPORTANT FACTOR OF MORBIDITY AND MORTALITY IN THE EXTREMELY PRETERM INFANT. PART I: BASICS OF IMMUNOLOGYReview article