2025-11-182025-11-18https://repositorio.uandes.cl/handle/uandes/59774<p>Inflammatory response, frequently associated with extreme preterm birth, has a relevant role in outcome, since immaturity of immune system, in such conditions, does not allow an appropriate modulation of these processes leading to sustained inflammation, to secondary damage and thus promoting short-medium- and long-term sequelae. Objective: to review immunological mechanisms involved in extreme prematurity, their effects on the most relevant systems and new therapeutical approaches.</p>info:eu-repo/semantics/openAccessFollow-upPerinatal InflammationPrematurityPreterm InfantSustained InflammationSyndromeReview article