Distribution and Frequency of Salivary Gland Tumours: an International Multicenter Study

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dc.coverageDOI: 10.1007/s12105-022-01459-0
dc.creatorAlsanie, Ibrahim
dc.creatorRajab, Shahad
dc.creatorCottom, Hannah
dc.creatorAdegun, Oluyori
dc.creatorAgarwal, Reshma
dc.creatorJay, Amrita
dc.creatorGraham, Laura
dc.creatorJames, Jacqueline
dc.creatorBarrett, A. William
dc.creatorvan Heerden, Willie
dc.creatorde Vito, Mariano
dc.creatorCanesso, Alessandra
dc.creatorAdisa, Akinyele Olumuyiwa
dc.creatorAkinshipo, Abdul-Warith Olaitan
dc.creatorAjayi, Oluseyi Folake
dc.creatorNwoga, Mark Chukwuemeka
dc.creatorOkwuosa, Chukwubuzor Udokwu
dc.creatorOmitola, Olufemi Gbenga
dc.creatorOrikpete, Efetobo Victor
dc.creatorSoluk-Tekkesin, Merva
dc.creatorBello, Ibrahim O.
dc.creatorQannam, Ahmed
dc.creatorGonzález-Arriagada, Wilfredo Alejandro
dc.creatorPérez-de-Oliveira, Maria Eduarda
dc.creatorSantos-Silva, Alan Roger
dc.creatorVargas, Pablo Agustin
dc.creatorToh, Eu-Wing
dc.creatorKhurram, Syed Ali
dc.date2022
dc.date.accessioned2025-11-18T19:41:58Z
dc.date.available2025-11-18T19:41:58Z
dc.descriptionBackground Salivary gland tumours (SGT) are a relatively rare group of neoplasms with a wide range of histopathological appearance and clinical features. To date, most of the epidemiological studies on salivary gland tumours are limited for a variety of reason including being out of date, extrapolated from either a single centre or country studies, or investigating either major or minor glands only. Methods This study aimed to mitigate these shortcomings by analysing epidemiological data including demographic, anatomical location and histological diagnoses of SGT from multiple centres across the world. The analysed data included age, gender, location and histological diagnosis from fifteen centres covering the majority of the world health organisation (WHO) geographical regions between 2006 and 2019. Results A total of 5739 cases were analysed including 65% benign and 35% malignant tumours. A slight female predilection (54%) and peak incidence between the fourth and seventh decade for both benign and malignant tumours was observed. The majority (68%) of the SGT presented in major and 32% in the minor glands. The parotid gland was the most common location (70%) for benign and minor glands (47%) for malignant tumours. Pleomorphic adenoma (70%), and Warthin’s tumour (17%), were the most common benign tumours whereas mucoepidermoid carcinoma (26%) and adenoid cystic carcinoma (17%) were the most frequent malignant tumours. Conclusions This multicentre investigation presents the largest cohort study to date analysing salivary gland tumour data from tertiary centres scattered across the globe. These findings should serve as a baseline for future studies evaluating the epidemiological landscape of these tumourseng
dc.identifierhttps://investigadores.uandes.cl/en/publications/8566e271-740a-4b4f-943f-584aa3c85137
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/52105
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.16 (2022) date: 2022-05-27 nr.4 p.1043-1054
dc.subjectSalivary gland tumours
dc.subjectSalivary gland neoplasms
dc.subjectHead and neck
dc.subjectMulticentre research study
dc.subjectDemographics
dc.subjectEpidemiology
dc.subjectSite distribution
dc.subjectHistological diagnosis
dc.titleDistribution and Frequency of Salivary Gland Tumours: an International Multicenter Studyeng
dc.typeArticleeng
dc.typeArtículospa
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