Towards closing socio-economic status disparities in COVID-19 premature mortality: a nationwide and trend analysis in Chile

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dc.coverageDOI: 10.1093/ije/dyad183
dc.creatorMaureira, Lea
dc.creatorUrquidi, Cinthya
dc.creatorSepúlveda-Peñaloza, Alejandro
dc.creatorSoto-Marchant, Mario
dc.creatorMatus, Patricia
dc.date2024
dc.date.accessioned05-01-2026 18:05
dc.date.available05-01-2026 18:05
dc.description<p>Background: Socio-economic status (SES) disparities in coronavirus disease 2019 (COVID-19) mortality have been reported but complete information and time trends are scarce. In this study, we analysed the years of life lost (YLL) due to COVID-19 premature mortality during the pandemic in Chile and its evolution according to SES and sex compared with a counterfactual scenario [cerebrovascular accidents (stroke)]. Method: We used Chile’s national mortality databases from 2020 to 2022. YLL and age-standardized YLL and mortality rates by sex and by epidemic waves were determined. The 346 communes were stratified into SES groups according to their poverty index quintile. Negative binomial regression models were used to test trends. Results: In &gt;2 years of the pandemic, the COVID-19 YLL was 975 937, corresponding to 61 174 deaths. The YLL rate per 100 000 inhabitants was 1027 for males and 594 for females. There was a heterogeneous distribution of YLL rates and the regional level. Communes in the most advantaged SES quintile (Q5) had the highest YLL during the first wave compared with those in the lowest SES quintile (Q1) (P &lt; 0.001) but the opposite was true during the second wave. COVID-19 YLL trends declined and differences between Q1 and Q2 vs Q5 converged from the second to the fourth waves (0.33 and 0.15, P<sub>trend</sub> &lt; 0.001 and P<sub>trend</sub> ¼ 0.024). YLL declined but differences persisted in stroke (–0.002, P<sub>trend</sub> ¼ 0.979). Conclusions: COVID-19 deaths resulted in a higher impact on premature death in Chile, especially in men, with a heterogeneous geographic distribution along the territory. SES and sex disparities in COVID-19 premature mortality had narrowed by the end of the pandemic.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/9d2f1923-0182-4ae6-ac86-a090b99a23a0
dc.languageeng
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourcevol.53 (2024) date: 2024-02-01 nr.1 p.1-8
dc.subjectCOVID-19
dc.subjectOmpact
dc.subjectPremature mortality
dc.subjectSocio-economic status disparities
dc.subjectYears of life lost
dc.subjectSDG 3 - Good Health and Well-being
dc.titleTowards closing socio-economic status disparities in COVID-19 premature mortality: a nationwide and trend analysis in Chileeng
dc.typeArticleeng
dc.typeArtículospa
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