The use of leucocyte and platelet-rich fibrin in socket management and ridge preservation: a split-mouth, randomized, controlled clinical trial

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dc.coverageDOI: 10.1111/jcpe.12612
dc.creatorTemmerman, Andy
dc.creatorVandessel, Jeroen
dc.creatorCastro, Ana
dc.creatorJacobs, Reinhilde
dc.creatorTeughels, Wim
dc.creatorPinto, Nelson
dc.creatorQuirynen, Marc
dc.date2016
dc.date.accessioned2025-11-18T19:47:20Z
dc.date.available2025-11-18T19:47:20Z
dc.description<p>AIM: To investigate the influence of the use L-PRF as a socket filling material and its ridge preservation properties.</p><p>MATERIALS AND METHODS: Twenty-two patients in need of single bilateral and closely symmetrical tooth extractions in the maxilla or mandible were included in a split-mouth RCT. Treatments were randomly assigned (L-PRF socket filling versus natural healing). CBCT scans were obtained after tooth extraction and three months. Scans were evaluated by superimposition using the original DICOM data. Mean ridge width differences between timepoints were measured at three levels below the crest on both the buccal and lingual sides (crest -1 mm (primary outcome variable), -3 mm and -5 mm).</p><p>RESULTS: Mean vertical height changes at the buccal were -1.5 mm (±1.3) for control sites and 0.5 mm (±2.3) for test sites (p &lt; 0.005). At the buccal side, control sites values were, respectively, -2.1 (±2.5), -0.3 mm (±0.3) (p &lt; 0.005) and -0.1 mm (±0.0), and test sites values were, respectively, -0.6 mm (±2.2) (p &lt; 0.005), -0.1 mm (±0.3) and 0.0 mm (±0.1). Significant differences (p &lt; 0.005) were found for total width reduction between test (-22.84%) and control sites (-51.92%) at 1 mm below crest level. Significant differences were found for socket fill (visible mineralized bone) between test (94.7%) and control sites (63.3%).</p><p>CONCLUSION: The use of L-PRF as a socket filling material to achieve preservation of horizontal and vertical ridge dimension at three  months after tooth extraction is beneficial.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/ce626b30-9fc9-4f6d-88fb-54177bf900c1
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/54991
dc.languageeng
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.sourcevol.43 (2016) date: 2016-11-01 nr.11 p.990-999
dc.subjectL-PRF
dc.subjectbone resorption
dc.subjectextraction socket
dc.subjectoral implant
dc.subjectplatelet concentrates
dc.subjectridge preservation
dc.titleThe use of leucocyte and platelet-rich fibrin in socket management and ridge preservation: a split-mouth, randomized, controlled clinical trialeng
dc.typeArticleeng
dc.typeArtículospa
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