Insights into incipient oral squamous cell carcinoma: a comprehensive south-american study

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dc.coverageDOI: 10.4317/medoral.26551
dc.creatorSaldivia-Siracusa, Cristina
dc.creatorAraújo, Anna Luíza Damaceno
dc.creatorArboleda, Lady Paola Aristizabal
dc.creatorAbrantes, Thamiris
dc.creatorPinto, Mariana Bitu Ramos
dc.creatorMendonça, Nathalia
dc.creatorCordero-Torres, Karina
dc.creatorGilligan, Gerardo
dc.creatorPiemonte, Eduardo
dc.creatorPanico, Rene
dc.creatorDe-Abreu-álves, Fábio
dc.creatorVillaroel-Dorrego, Mariana
dc.creatorRomañach, Mário José
dc.creatorAbrahão, Aline Corrêa
dc.creatorGonzález-Arriagada, Wilfredo Alejandro
dc.creatorHunter, Keith D.
dc.creatorRibeiro, Ana Carolina Prado
dc.creatorLopes, Marcio Ajudarte
dc.creatorVargas, Pablo Agustin
dc.creatorSantos-Silva, Alan Roger
dc.date2024
dc.date.accessioned2025-11-18T19:43:25Z
dc.date.available2025-11-18T19:43:25Z
dc.description<p>Background: To describe demographic and clinicopathological aspects of a South-American cohort of incipient oral squamous cell carcinoma patients. Material and Methods: A cross-sectional, observational study was performed to assess demographic and clinicopathological characteristics of incipient oral squamous cell carcinoma patients from 6 South-American institutions. Results: One hundred and seven patients within the histopathological spectrum of incipient oral squamous cell carcinoma (in-situ and microinvasive) were included. Fifty-eight (54.2%) patients were men with a mean age of 60.69 years. Forty-nine (45.8%) and thirty-nine (36.5%) patients had history of tobacco and alcohol use, respectively. Clinically, most of the lesions were plaques (82.2%), ≥ 2 cm in extension (72%), affecting the lateral border of the tongue (55.1%), and soft palate (12.1%) with a mixed (white and red) appearance. Eighty-two (76.7%) lesions were predominantly white and 25 (23.3%) predominantly red. Conclusions: To the best of our knowledge, this is the largest cohort of incipient oral squamous cell carcinoma patients, which raises awareness of clinicians’ inspection acuteness by demonstrating the most frequent clinical aspects of this disease, potentially improving oral cancer secondary prevention strategies.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/4995640b-6512-4021-929c-9fabe61bff58
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/52864
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.29 (2024) nr.4 p.e575-e583
dc.subjectMouth neoplasm
dc.subjectcarcinoma in-situ
dc.subjectdiagnosis
dc.subjectmicroinvasive
dc.subjectoral squamous cell carcinoma
dc.subjectCarcinoma, Squamous Cell/epidemiology
dc.subjectSouth America/epidemiology
dc.subjectCross-Sectional Studies
dc.subjectHumans
dc.subjectMouth Neoplasms/epidemiology
dc.subjectMiddle Aged
dc.subjectMale
dc.subjectAged, 80 and over
dc.subjectFemale
dc.subjectAdult
dc.subjectAged
dc.subjectSDG 3 - Good Health and Well-being
dc.titleInsights into incipient oral squamous cell carcinoma: a comprehensive south-american studyeng
dc.typeArticleeng
dc.typeArtículospa
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