The effects of aging on semen parameters and sperm DNA fragmentation

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dc.coverageDOI: 10.5935/1518-0557.20190058
dc.creatorPino, Víctor
dc.creatorSanz, Antonia
dc.creatorValdés, Nicolás
dc.creatorCrosby, Javier
dc.creatorMackenna, Antonio
dc.date2020
dc.date.accessioned2025-11-18T19:45:25Z
dc.date.available2025-11-18T19:45:25Z
dc.description<p>Introduction: This study aimed to look into possible correlations between male age and different sperm parameters derived from semen analysis and sperm deoxyribonucleic acid (DNA) fragmentation. Methods: This retrospective descriptive study included 2681 male patients who underwent semen analysis at Clínica Las Condes (CLC), Santiago, Chile, between January 2014 and May 2017; correlations between age and sperm parameters were analyzed. Results: Males above the age of 50 were significantly more likely to present anomalies in semen volume, sperm concentration, and sperm DNA fragmentation; males aged 41+ years were more likely to have lower sperm concentration levels; males aged 31+ years were more likely to have decreased sperm motility; when concentration was constant, more volume and motility anomalies were seen as age increased; when volume was kept constant, more motility and concentration anomalies were seen as age increased; and when motility was constant, normal semen volumes decreased as age increased. Conclusion: Our study showed that male age significantly affects sperm parameters that might have an impact on male fertility.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/e2eb8be1-ee3f-4e95-88b4-cea11deb5aa3
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/53956
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.24 (2020) nr.1 p.82-86
dc.subjectAging
dc.subjectFertility
dc.subjectInfertility
dc.subjectPaternal age
dc.subjectSemen analysis
dc.subjectSperm DNA fragmentation
dc.titleThe effects of aging on semen parameters and sperm DNA fragmentationeng
dc.typeArticleeng
dc.typeArtículospa
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