Role of platelet-rich plasma in the treatment of rotator cuff tendinopathy

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dc.coverageDOI: 10.5312/wjo.v14.i7.505
dc.creatorGarcia, Ausberto Velasquez
dc.creatorMartini, Liborio Ingala
dc.creatorAbache, Andres Franco
dc.creatorAbdo, Glen
dc.date2023
dc.date.accessioned2025-11-18T19:45:56Z
dc.date.available2025-11-18T19:45:56Z
dc.description<p>Shoulder pain is a common musculoskeletal complaint, and rotator cuff (RC) pathologies are one of the main causes. The RC undergoes various tendinopathic and avascular changes during the aging process. Other degenerative changes affecting its healing potential make it an appealing target for biological agents. Platelet-rich plasma (PRP) has demonstrated the potential to deliver a high concentration of several growth factors and anti-inflammatory mediators, and its clinical use is mainly supported by experiments that demonstrated its positive effect on muscle, ligaments, and tendinous cells. This review aimed to specify the role of PRP and its future applications in RC tendinopathies based on the current clinical evidence. Due to the different characteristics and conflicting outcomes, clinicians should use PRP with moderate expectations until more consistent evidence is available. However, it is reasonable to consider PRP in patients with contraindications to corticosteroid injections or those with risk factors for inadequate healing. Its autologous origin makes it a safe treatment, and its characteristics make it a promising option for treating RC tendinopathy, but the efficacy has yet to be established.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/9edc3f64-124a-4531-aa0b-8b576a5ad00f
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/54236
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.14 (2023) nr.7 p.505-515
dc.subjectInjectables
dc.subjectNonoperative treatment
dc.subjectPlatelet-rich plasma
dc.subjectRotator cuff
dc.subjectShoulder pain
dc.subjectTendinopathy
dc.titleRole of platelet-rich plasma in the treatment of rotator cuff tendinopathyeng
dc.typeReview articleeng
dc.typeArtículo de revisiónspa
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