La humedad previene la formación inducida por el ejercicio de peróxido de hidrógeno y nitrito en el condensado del aire exhalado en ciclistas recreativos

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dc.coverageDOI: 10.1007/s00421-020-04456-9
dc.creatorContreras-Briceño, Felipe
dc.creatorEspinosa-Ramirez, Maximiliano
dc.creatorViscor, Ginés
dc.creatorAraneda, Oscar F.
dc.date2020
dc.date.accessioned2025-11-18T19:40:27Z
dc.date.available2025-11-18T19:40:27Z
dc.description<p>Purpose: The aerobic exercise affects the respiratory redox-state. The influence of different relative humidity (RH) levels on the formation of respiratory reactive chemical species associated with redox-state altered by exercise has been poorly explored. Our aim was to evaluate the effect of two different RH conditions (40% vs. 90%) on the concentration of hydrogen peroxide and nitrite in exhaled breath condensate ([H<sub>2</sub>O<sub>2</sub>]<sub>EBC</sub> and [NO<sub>2</sub><sup>−</sup>]<sub>EBC</sub>) and spirometry parameters in recreational cyclists. Methods: Sixteen men and women (12/4) (mean age ± SD: 23.5 ± 2.2 years) completed 60-min of cycling at 166.3 ± 26.9 watts (70% of maximum load of V ˙ O <sub>2</sub>-max. test, 49.3 ± 7.6 mL·min<sup>−1</sup>·kg<sup>−1</sup>) at random 40%-RH and 90%-RH conditions separated by 7 days. The two-way RM-ANOVA test was applied to compare [H<sub>2</sub>O<sub>2</sub>]<sub>EBC</sub>, [NO<sub>2</sub><sup>−</sup>]<sub>EBC</sub>, [NO<sub>2</sub><sup>−</sup>]<sub>EBC</sub>/[NO<sub>2</sub><sup>−</sup>]<sub>Plasma</sub> at rest and 80-min post-exercise (80-post); and spirometry parameters at rest, 20-post and 80-post. Results: The interaction of factors (humidity × time) was significant in [H<sub>2</sub>O<sub>2</sub>]<sub>EBC</sub>, [NO<sub>2</sub><sup>−</sup>]<sub>EBC</sub>, [NO<sub>2</sub><sup>−</sup>]<sub>EBC</sub>/[NO<sub>2</sub><sup>−</sup>]<sub>Plasma</sub> (p = 0.005, p = 0.030, p = 0.043, respectively). At 40%-RH conditions, the same parameters were higher in 80-post than at rest (p &lt; 0.001, p = 0.001, p = 0.014, respectively). At the same time, the [H<sub>2</sub>O<sub>2</sub>]<sub>EBC</sub> and [NO<sub>2</sub><sup>−</sup>]<sub>EBC</sub>/[NO<sub>2</sub><sup>−</sup>]<sub>Plasma</sub> were higher in 40%-RH than 90%-RH (p = 0.010, p &lt; 0.001, respectively). The interaction was significant in FEV<sub>1</sub> (p = 0.013) and FEF<sub>25-75%</sub> (p = 0.023), but not in FEV<sub>1</sub>/FVC (p = 0.362). At 80-post, the changes are kept in 90%-RH (p &lt; 0.001), diminishing in 40%-RH being similar to rest. Conclusion: In recreational cyclists, 90%-RH prevents the increase of hydrogen peroxide and nitrite in exhaled breath condensate samples observed at 40%-RH and prolonging the bronchodilation until 80-post cycling exercise.</p>eng
dc.descriptionThe aerobic exercise affects the respiratory redox-state. The influence of different relative humidity (RH) levels on the formation of respiratory reactive chemical species associated with redox-state altered by exercise has been poorly explored. Our aim was to evaluate the effect of two different RH conditions (40% vs. 90%) on the concentration of hydrogen peroxide and nitrite in exhaled breath condensate ([H2O2]EBC and [NO2<sup style="box-sizing: inherit; color: rgb(34, 34, 34); font-family: Merriweather, serif;">−</sup>]EBC) and spirometry parameters in recreational cyclists.spa
dc.identifierhttps://investigadores.uandes.cl/en/publications/3dd635da-6d96-461a-aeeb-15bc8baaea6c
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/51303
dc.languageeng
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourcevol.120 (2020) date: 2020-10-01 nr.10 p.2339-2348
dc.subjectBronchodilation
dc.subjectExercise
dc.subjectExhaled breath condensate
dc.subjectHumidity
dc.subjectOxidative stress
dc.subjectBroncodilatación
dc.subjectEjercicio
dc.subjectCondensado de aliento exhalado
dc.subjectHumedad
dc.subjectEstrés oxidativo
dc.subjectSDG 3 - Good Health and Well-being
dc.titleLa humedad previene la formación inducida por el ejercicio de peróxido de hidrógeno y nitrito en el condensado del aire exhalado en ciclistas recreativosspa
dc.titleHumidity prevents the exercise-induced formation of hydrogen peroxide and nitrite in exhaled breath condensate in recreational cyclistseng
dc.typeArticleeng
dc.typeArtículospa
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