MRI is the most commonly used imaging modality for HCC screening at a tertiary care transplant center

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dc.coverageDOI: 10.1007/s00261-021-03212-7
dc.creatorHernandez-Meza, Gabriela
dc.creatorVioli, Naik Vietti
dc.creatorSaid, Daniela
dc.creatorNovogrodsky, Eitan
dc.creatorVillavisanis, Dillan
dc.creatorMaron, Samuel Z.
dc.creatorFrere, Justin
dc.creatorSchiano, Thomas D.
dc.creatorFriedman, Scott
dc.creatorBoffetta, Paolo
dc.creatorBranch, Andrea
dc.creatorTaouli, Bachir
dc.date2021
dc.date.accessioned2025-11-18T19:45:34Z
dc.date.available2025-11-18T19:45:34Z
dc.description<p>Purpose: In this study, we describe the patterns of hepatocellular carcinoma (HCC) screening with imaging and factors associated with imaging modality selection in a tertiary care transplant center. Methods: This was a retrospective study where all adult patients with cirrhosis and/or chronic hepatitis B virus infection referred for HCC screening with ultrasound (US), CT or MRI were identified during 2017. The association between imaging methods, demographic/clinical data were analyzed by uni- and multivariate analysis. Results: A total of 1437 patients were included (median age 61y, 59% male, median BMI 27.5 kg/m<sup>2</sup>, median AFP 3.4 ng/mL, 37% with HCV and 87% with cirrhosis). Index screening imaging method utilization included MRI (51%), US (33%) and CT (16%). Use of US as the index imaging modality for screening was significantly associated with race/ethnicity [Odds Ratio (OR) 1.71–2.01, all p &lt; 0.05] in multivariate analysis. Presence of cirrhosis (OR 0.29, p &lt; 0.001) and referral by a hepatologist (OR 0.23, p &lt; 0.001) were associated with screening with MRI in the multivariate analysis; while gender, age, BMI, etiology and income at ZIP code of residence were not significantly associated with imaging modality selection. HCC was observed in 62 patients (prevalence 4.3%). Rate of HCC detection was significantly higher with MRI vs US (5.9% vs. 1.5%, p = 0.001). Conclusion: MRI was the most frequently used modality (&gt; 50%) for HCC screening in our tertiary care center, in contrast with the current practice guidelines. Race/ethnicity, cirrhosis and referral by a hepatologist were associated with the imaging method used for HCC screening.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/4367b97a-5de7-4a59-ad39-7175e36303ac
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/54040
dc.languageeng
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourcevol.46 (2021) nr.11 p.5142-5151
dc.subjectHepatocellular carcinoma
dc.subjectMagnetic Resonance Imaging
dc.subjectScreening
dc.subjectUltrasonography
dc.subjectSDG 3 - Good Health and Well-being
dc.titleMRI is the most commonly used imaging modality for HCC screening at a tertiary care transplant centereng
dc.typeArticleeng
dc.typeArtículospa
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