The Role of Long Non-Coding RNAs in Trophoblast Regulation in Preeclampsia and Intrauterine Growth Restriction

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dc.coverageDOI: 10.3390/genes12070970
dc.creatorMonteiro, Lara
dc.creatorPeñailillo, Reyna
dc.creatorSánchez, Mario
dc.creatorAcuña-Gallardo, Stephanie
dc.creatorMönckeberg, Max
dc.creatorOng, Judith
dc.creatorChoolani, Mahesh
dc.creatorIllanes, Sebastián
dc.creatorNardocci, Gino
dc.date2021
dc.date.accessioned2025-11-18T19:47:51Z
dc.date.available2025-11-18T19:47:51Z
dc.description<p>Preeclampsia (PE) and Intrauterine Growth Restriction (IUGR) are two pregnancy-specific placental disorders with high maternal, fetal, and neonatal morbidity and mortality rates worldwide. The identification biomarkers involved in the dysregulation of PE and IUGR are fundamental for developing new strategies for early detection and management of these pregnancy pathologies. Several studies have demonstrated the importance of long non-coding RNAs (lncRNAs) as essential regulators of many biological processes in cells and tissues, and the placenta is not an exception. In this review, we summarize the importance of lncRNAs in the regulation of trophoblasts during the development of PE and IUGR, and other placental disorders.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/8c57eea5-6d18-4a05-912a-48b8a005c52e
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/55259
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.12 (2021) date: 2021-06-01 nr.7
dc.subjectIntrauterine growth restriction
dc.subjectLong non-coding RNAs
dc.subjectPreeclampsia
dc.titleThe Role of Long Non-Coding RNAs in Trophoblast Regulation in Preeclampsia and Intrauterine Growth Restrictioneng
dc.typeArticleeng
dc.typeArtículospa
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