Coarse Particulate Air Pollution and Daily Mortality A Global Study in 205 Cities

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dc.coverageDOI: 10.1164/rccm.202111-2657OC
dc.creatorLiu, Cong
dc.creatorCai, Jing
dc.creatorChen, Renjie
dc.creatorSera, Francesco
dc.creatorGuo, Yuming
dc.creatorTong, Shilu
dc.creatorLi, Shanshan
dc.creatorLavigne, Eric
dc.creatorCorrea, Patricia Matus
dc.creatorOrtega, Nicolas Valdes
dc.creatorOrru, Hans
dc.creatorMaasikmets, Marek
dc.creatorJaakkola, Jouni J.K.
dc.creatorRyti, Niilo
dc.creatorBreitner, Susanne
dc.creatorSchneider, Alexandra
dc.creatorKatsouyanni, Klea
dc.creatorSamoli, Evangelia
dc.creatorHashizume, Masahiro
dc.creatorHonda, Yasushi
dc.creatorNg, Chris Fook Sheng
dc.creatorDiaz, Magali Hurtado
dc.creatorDe la Cruz Valencia, César
dc.creatorRao, Shilpa
dc.creatorPalomares, Alfonso Diz Lois
dc.creatorda Silva, Susana Pereira
dc.creatorMadureira, Joana
dc.creatorHolobâc, Iulian Horia
dc.creatorFratianni, Simona
dc.creatorScovronick, Noah
dc.creatorGarland, Rebecca M.
dc.creatorTobias, Aurelio
dc.creatorIñiguez, Carmén
dc.creatorForsberg, Bertil
dc.creatorÅstrom, Christofer
dc.creatorVicedo-Cabrera, Ana Maria
dc.creatorRagettli, Martina S.
dc.creatorGuo, Yue Liang Leon
dc.creatorPan, Shih Chun
dc.creatorMilojevic, Ai
dc.creatorBell, Michelle L.
dc.creatorZanobetti, Antonella
dc.creatorSchwartz, Joel
dc.creatorGasparrini, Antonio
dc.creatorKan, Haidong
dc.date2022
dc.date.accessioned2025-11-18T19:44:23Z
dc.date.available2025-11-18T19:44:23Z
dc.description<p>Rationale: The associations between ambient coarse particulate matter (PM<sub>2.5–10</sub>) and daily mortality are not fully understood on a global scale. Objectives: To evaluate the short-term associations between PM<sub>2.5–10</sub> and total, cardiovascular, and respiratory mortality across multiple countries/regions worldwide. Methods: We collected daily mortality (total, cardiovascular, and respiratory) and air pollution data from 205 cities in 20 countries/regions. Concentrations of PM<sub>2.5–10</sub> were computed as the difference between inhalable and fine PM. A two-stage time-series analytic approach was applied, with overdispersed generalized linear models and multilevel meta-analysis. We fitted two-pollutant models to test the independent effect of PM<sub>2.5–10</sub> from copollutants (fine PM, nitrogen dioxide, sulfur dioxide, ozone, and carbon monoxide). Exposure–response relationship curves were pooled, and regional analyses were conducted. Measurements and Main Results: A 10 μg/m<sup>3</sup> increase in PM<sub>2.5–10</sub> concentration on lag 0–1 day was associated with increments of 0.51% (95% confidence interval [CI], 0.18%–0.84%), 0.43% (95% CI, 0.15%–0.71%), and 0.41% (95% CI, 0.06%–0.77%) in total, cardiovascular, and respiratory mortality, respectively. The associations varied by country and region. These associations were robust to adjustment by all copollutants in two-pollutant models, especially for PM<sub>2.5</sub>. The exposure–response curves for total, cardiovascular, and respiratory mortality were positive, with steeper slopes at lower exposure ranges and without discernible thresholds. Conclusions: This study provides novel global evidence on the robust and independent associations between short-term exposure to ambient PM<sub>2.5–10</sub> and total, cardiovascular, and respiratory mortality, suggesting the need to establish a unique guideline or regulatory limit for daily concentrations of PM<sub>2.5–10</sub></p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/579442de-90a1-4726-8aba-ec2e27d46e35
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/53380
dc.languageeng
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourcevol.206 (2022) date: 2022-10-01 nr.8 p.999-1007
dc.subjectPM
dc.subjectair pollution
dc.subjectmortality
dc.subjectmulticenter study
dc.subjecttime-series study
dc.subjectSDG 11 - Sustainable Cities and Communities
dc.titleCoarse Particulate Air Pollution and Daily Mortality A Global Study in 205 Citieseng
dc.typeArticleeng
dc.typeArtículospa
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