Actualización en el diagnóstico y manejo de la Infección por Clostridioides difficile

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dc.coverageDOI: 10.4067/s0034-98872023000700887
dc.creatorvon Muhlenbrock, Christian
dc.creatorNúñez, Paulina
dc.creatorEspinoza, Ricardo
dc.creatorQuera, Rodrigo
dc.date2023
dc.date.accessioned2025-11-18T19:50:07Z
dc.date.available2025-11-18T19:50:07Z
dc.description<p>Clostridioides difficile (C. difficile) is one of the leading causes of infection associated with health care with high morbidity and mortality, especially among hospitalized older adults. The increase in the use of antibiotics has been associated with a higher number of cases and greater virulence. Its clinical presentation ranges from asymptomatic carriers to toxic megacolon. Studies with stool tests (glutamate dehydrogenase, toxins A and B, and nuclear acid amplification techniques) should be considered in these cases. Fidaxomicin, fecal microbiota transplant, and new therapies such as monoclonal antibodies have been incorporated into the therapeutic arsenal, with a higher level of evidence. Nevertheless, the severity, patient comorbidity, recurrence risk factors, and the economic cost of each therapeutic option must be considered. This review aims to update the last guidelines proposed by the Chilean Societies of Gastroenterology and Infectious Diseases published in 2016, providing the latest recommendations regarding prevention, diagnosis, and treatment of C. difficile infection.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/a4603d67-2a70-4aa7-83ca-3d8175c94159
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/56444
dc.languagespa
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.151 (2023) nr.7 p.887-898
dc.subjectClostridioides
dc.subjectDiagnosis
dc.subjectRecurrence
dc.subjectTreatment
dc.subjectSDG 3 - Good Health and Well-being
dc.titleActualización en el diagnóstico y manejo de la Infección por Clostridioides difficilespa
dc.titleUpdate in diagnosis and management of Clostridioides difficileeng
dc.typeArticleeng
dc.typeArtículospa
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