Effect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trial

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dc.coverageDOI: 10.1111/jcpe.12991
dc.creatorQuintero, Antonio J.
dc.creatorChaparro, Alejandra
dc.creatorQuirynen, Marc
dc.creatorRamirez, Valeria
dc.creatorPrieto, Diego
dc.creatorMorales, Helia
dc.creatorPrada, Pamela
dc.creatorHernández, Macarena
dc.creatorSanz, Antonio
dc.date2018
dc.date.accessioned2025-11-18T19:47:40Z
dc.date.available2025-11-18T19:47:40Z
dc.description<p>Aim: To evaluate the impact of two non-surgical periodontal treatment modalities on metabolic and periodontal clinical parameters in subjects with type 2 diabetes mellitus (T2DM) and poor glycaemic control and chronic periodontitis. Material and methods: A randomized controlled clinical trial was conducted. Ninety-three T2DM subjects with glycosylated haemoglobin (HbA1c) &gt; 7% were randomly assigned to one of two groups receiving scaling with root planing in multiple sessions quadrant-by-quadrant (Q by Q) or within 24 hr (one stage). Periodontal parameters, HbA1c, glycaemia blood levels (FPG) and C-reactive protein (CRP) values were assessed at baseline and at 3 and 6 months post-therapy. Results: At 6 months, HbA1c had decreased by 0.48% in the Q by Q group and by 0.18% in the one-stage group (p = 0.455). After therapy, subjects with an initial HbA1c &lt; 9% showed an increase of 0.31% (p = 0.145), compared with a decrease of 0.88% (p = 0.006) in those with an initial HbA1c ≥ 9%. Periodontal parameters improved significantly (p &lt; 0.0001) post-therapy, with similar results for both treatment modalities. Conclusion: Periodontal therapy had the greatest impact on HbA1c reduction on patients with an HbA1c &gt; 9% regardless of treatment modality. Both modalities resulted in significant improvements in periodontal parameters.</p>eng
dc.descriptionAim: To evaluate the impact of two non-surgical periodontal treatment modalities on metabolic and periodontal clinical parameters in subjects with type 2 diabetes mellitus (T2DM) and poor glycaemic control and chronic periodontitis. Material and methods: A randomized controlled clinical trial was conducted. Ninety-three T2DM subjects with glycosylated haemoglobin (HbA1c) &gt; 7% were randomly assigned to one of two groups receiving scaling with root planing in multiple sessions quadrant-by-quadrant (Q by Q) or within 24 hr (one stage). Periodontal parameters, HbA1c, glycaemia blood levels (FPG) and C-reactive protein (CRP) values were assessed at baseline and at 3 and 6 months post-therapy. Results: At 6 months, HbA1c had decreased by 0.48% in the Q by Q group and by 0.18% in the one-stage group (p = 0.455). After therapy, subjects with an initial HbA1c &lt; 9% showed an increase of 0.31% (p = 0.145), compared with a decrease of 0.88% (p = 0.006) in those with an initial HbA1c ≥ 9%. Periodontal parameters improved significantly (p [removed] 9% regardless of treatment modality. Both modalities resulted in significant improvements in periodontal parameters. © 2018 John Wiley &amp; Sons A/S. Published by John Wiley &amp; Sons Ltdspa
dc.identifierhttps://investigadores.uandes.cl/en/publications/d447aebf-bb35-4bd2-b48b-c7a57424fa59
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/55158
dc.languageeng
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourcevol.45 (2018) nr.9 p.1098-1106
dc.subjectC-reactive protein
dc.subjectglycosylated haemoglobin
dc.subjectperiodontal treatment
dc.subjectperiodontitis
dc.subjecttype 2 diabetes mellitus
dc.titleEffect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trialeng
dc.typeArticleeng
dc.typeArtículospa
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