Gastric dysrhythmias in patients with early systemic sclerosis: a cross-sectional study

Simple item page
dc.coverageDOI: 10.1093/rap/rkae041
dc.creatorSeelmann, Daniela
dc.creatorPoblete, Marıa Paz
dc.creatorSaavedra, Silvana
dc.creatorMadrid, Ana Marıa
dc.creatorvon Muhlenbrock, Christian
dc.creatorEstay, Camila
dc.creatorGoecke, Annelise
dc.date2024
dc.date.accessioned2025-11-18T19:46:07Z
dc.date.available2025-11-18T19:46:07Z
dc.description<p>Objectives: Gastric involvement in patients with early systemic sclerosis (SSc) has not been previously investigated. We aim to evaluate the association of gastric dysrhythmias with gastrointestinal (GI) symptoms and nailfold video capillaroscopy (NVC). Methods: Cross-sectional study. Patients with early SSc, completed the UCLA GIT 2.0 questionnaire, performed an NVC, and a surface Electrogastrography (EGG). Descriptive statistics was used for demographic and clinical characteristics and Fisher and Kendall Tau tests were used for association analysis. Results: 75 patients were screened, 30 patients were consecutively enrolled, 29 performed the EGG and 1 patient had a non-interpretable NVC. 29/30 were female with a mean age of 48.7 years (25–72). The mean disease duration from the first non-RP symptom was 22.6 þ/-10.8 months and most of the patients had limited disease (76.6%). Total GIT 2.0 score symptoms were moderate-severe in 63% of the participants and 28/29 had an abnormal EGG. Bradygastria was the most common pattern present in 70% of the participants. NVC patterns: 17% early, 34% active, 28% scleroderma-like, 14% non-specific, and 2 patients had a normal NVC. There was no association between severe GI symptoms or NVC patterns and severely abnormal EGG, but the presence of bradygastria was associated with severe impairment in the social functioning area (p 0.018). Conclusions: Gastric dysmotility is common in early SSc and there is a lack of correlation between GI symptoms and NVC scleroderma patterns. EGG is a sensitive, cheap, and non-invasive exam, that may be an alternative to early diagnosis of GI involvement.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/c12b73fe-bcd1-4c9b-949c-93f64c3a7536
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/54332
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.8 (2024) nr.2
dc.titleGastric dysrhythmias in patients with early systemic sclerosis: a cross-sectional studyeng
dc.typeArticleeng
dc.typeArtículospa
Files
Collections
PURE