Mathematical Modeling for Pharmacokinetic Predictions from Controlled Drug Release Nano Systems: A comparative parametric study
| dc.coverage | DOI: 10.13005/bpj/1552 | |
| dc.creator | Haidar, Ziyad S. | |
| dc.date | 2018 | |
| dc.date.accessioned | 05-01-2026 18:19 | |
| dc.date.available | 05-01-2026 18:19 | |
| dc.description | <p>In the present work, several mathematical models well-known in the literature for simulating drug release kinetics are compared using available experimental data sets obtained in real systems with different drugs and nano-sized carriers. Herein, the ÷<sup>2</sup> minimization method, is employedconcluding that the Korsmeyer-Peppas modelprovides the best-ûtin all cases. Hence, (i) better understanding of the exact mass transport mechanism(s) involved in drug(s) release, and (ii) quantitative prediction of the drug release kinetics, can be computed.</p> | eng |
| dc.description | In the present work, several mathematical models well-known in the literature for simulating drug release kinetics are compared using available experimental data sets obtained in real systems with different drugs and nano-sized carriers. Herein, the ÷2 minimization method, is employedconcluding that the Korsmeyer-Peppas modelprovides the best-ûtin all cases. Hence, (i) better understanding of the exact mass transport mechanism(s) involved in drug(s) release, and (ii) quantitative prediction of the drug release kinetics, can be computed. | spa |
| dc.identifier | https://investigadores.uandes.cl/en/publications/a24713be-e37d-417f-becc-810612a9c9dc | |
| dc.language | eng | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | vol.11 (2018) date: 2018-12-28 nr.4 p.1801-1806 | |
| dc.subject | Drug dissolution | |
| dc.subject | Least squares method | |
| dc.subject | Mathematical modelling | |
| dc.subject | Model comparison | |
| dc.subject | Release kinetics | |
| dc.subject | Statistical analysis | |
| dc.subject | Drug dissolution | |
| dc.subject | Least squares method | |
| dc.subject | Mathematical modelling | |
| dc.subject | Model comparison | |
| dc.subject | Release kinetics | |
| dc.subject | Statistical analysis | |
| dc.title | Mathematical Modeling for Pharmacokinetic Predictions from Controlled Drug Release Nano Systems: A comparative parametric study | eng |
| dc.type | Article | eng |
| dc.type | Artículo | spa |