Surface functionalization of nanobiomaterials for application in stem cell culture, tissue engineering, and regenerative medicine

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dc.coverageDOI: 10.1002/btpr.2262
dc.creatorRana, Deepti
dc.creatorRamasamy, Keerthana
dc.creatorLeena, Maria
dc.creatorJiménez, Constanza
dc.creatorCampos, Javier
dc.creatorIbarra, Paula
dc.creatorHaidar, Ziyad S.
dc.creatorRamalingam, Murugan
dc.date2016
dc.date.accessioned2025-11-18T19:40:09Z
dc.date.available2025-11-18T19:40:09Z
dc.descriptionStem cell-based approaches offer great application potential in tissue engineering and regenerative medicine owing to their ability of sensing the microenvironment and respond accordingly (dynamic behavior). Recently, the combination of nanobiomaterials with stem cells has paved a great way for further exploration. Nanobiomaterials with engineered surfaces could mimic the native microenvironment to which the seeded stem cells could adhere and migrate. Surface functionalized nanobiomaterial-based scaffolds could then be used to regulate or control the cellular functions to culture stem cells and regenerate damaged tissues or organs. Therefore, controlling the interactions between nanobiomaterials and stem cells is a critical factor. However, surface functionalization or modification techniques has provided an alternative approach for tailoring the nanobiomaterials surface in accordance to the physiological surrounding of a living cells; thereby, enhancing the structural and functional properties of the engineered tissues and organs. Currently, there are a variety of methods and technologies available to modify the surface of biomaterials according to the specific cell or tissue properties to be regenerated. This review highlights the trends in surface modification techniques for nanobiomaterials and the biological relevance in stem cell-based tissue engineering and regenerative medicine.eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/88068d9d-6b7a-40f7-95b2-6cb7cbe200cd
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/51145
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.32 (2016) date: 2016-05-01 nr.3 p.554-567
dc.subjectmicroenvironment
dc.subjectnanobiomaterials
dc.subjectregenerative medicine
dc.subjectstem cells
dc.subjectsurface functionalization
dc.subjecttissue engineering
dc.subjectmicroenvironment
dc.subjectnanobiomaterials
dc.subjectregenerative medicine
dc.subjectstem cells
dc.subjectsurface functionalization
dc.subjecttissue engineering
dc.titleSurface functionalization of nanobiomaterials for application in stem cell culture, tissue engineering, and regenerative medicineeng
dc.typeScientific revieweng
dc.typeReseña científicaspa
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