Joint effect of heat and air pollution on mortality in 620 cities of 36 countries

dc.coverageDOI: 10.1016/j.envint.2023.108258
dc.creatorStafoggia, Massimo
dc.creatorMichelozzi, Paola
dc.creatorSchneider, Alexandra
dc.creatorArmstrong, Ben
dc.creatorScortichini, Matteo
dc.creatorRai, Masna
dc.creatorAchilleos, Souzana
dc.creatorAlahmad, Barrak
dc.creatorAnalitis, Antonis
dc.creatorÅström, Christofer
dc.creatorBell, Michelle L.
dc.creatorCalleja, Neville
dc.creatorKrage Carlsen, Hanne
dc.creatorCarrasco, Gabriel
dc.creatorPaul Cauchi, John
dc.creatorDSZS Coelho, Micheline
dc.creatorCorrea, Patricia M.
dc.creatorDiaz, Magali H.
dc.creatorEntezari, Alireza
dc.creatorForsberg, Bertil
dc.creatorGarland, Rebecca M.
dc.creatorLeon Guo, Yue
dc.creatorGuo, Yuming
dc.creatorHashizume, Masahiro
dc.creatorHolobaca, Iulian H.
dc.creatorÍñiguez, Carmen
dc.creatorJaakkola, Jouni J.K.
dc.creatorKan, Haidong
dc.creatorKatsouyanni, Klea
dc.creatorKim, Ho
dc.creatorKyselý, Jan
dc.creatorLavigne, Eric
dc.creatorLee, Whanhee
dc.creatorLi, Shanshan
dc.creatorMaasikmets, Marek
dc.creatorMadureira, Joana
dc.creatorMayvaneh, Fatemeh
dc.creatorFook Sheng Ng, Chris
dc.creatorNunes, Baltazar
dc.creatorOrru, Hans
dc.creatorV Ortega, Nicolás
dc.creatorOsorio, Samuel
dc.creatorPalomares, Alfonso D.L.
dc.creatorPan, Shih Chun
dc.creatorPascal, Mathilde
dc.creatorRagettli, Martina S.
dc.creatorRao, Shilpa
dc.creatorRaz, Raanan
dc.creatorRoye, Dominic
dc.creatorRyti, Niilo
dc.creatorHN Saldiva, Paulo
dc.creatorSamoli, Evangelia
dc.creatorSchwartz, Joel
dc.creatorScovronick, Noah
dc.creatorSera, Francesco
dc.creatorTobias, Aurelio
dc.creatorTong, Shilu
dc.creatorDLC Valencia, César
dc.creatorMaria Vicedo-Cabrera, Ana
dc.creatorUrban, Aleš
dc.creatorGasparrini, Antonio
dc.creatorBreitner, Susanne
dc.creatorde' Donato, Francesca K.
dc.date2023
dc.date.accessioned2025-11-18T19:44:23Z
dc.date.available2025-11-18T19:44:23Z
dc.description<p>Background: The epidemiological evidence on the interaction between heat and ambient air pollution on mortality is still inconsistent. Objectives: To investigate the interaction between heat and ambient air pollution on daily mortality in a large dataset of 620 cities from 36 countries. Methods: We used daily data on all-cause mortality, air temperature, particulate matter ≤ 10 μm (PM<sub>10</sub>), PM ≤ 2.5 μm (PM<sub>2.5</sub>), nitrogen dioxide (NO<sub>2</sub>), and ozone (O<sub>3</sub>) from 620 cities in 36 countries in the period 1995–2020. We restricted the analysis to the six consecutive warmest months in each city. City-specific data were analysed with over-dispersed Poisson regression models, followed by a multilevel random-effects meta-analysis. The joint association between air temperature and air pollutants was modelled with product terms between non-linear functions for air temperature and linear functions for air pollutants. Results: We analyzed 22,630,598 deaths. An increase in mean temperature from the 75<sup>th</sup> to the 99<sup>th</sup> percentile of city-specific distributions was associated with an average 8.9 % (95 % confidence interval: 7.1 %, 10.7 %) mortality increment, ranging between 5.3 % (3.8 %, 6.9 %) and 12.8 % (8.7 %, 17.0 %), when daily PM<sub>10</sub> was equal to 10 or 90 μg/m<sup>3</sup>, respectively. Corresponding estimates when daily O<sub>3</sub> concentrations were 40 or 160 μg/m<sup>3</sup> were 2.9 % (1.1 %, 4.7 %) and 12.5 % (6.9 %, 18.5 %), respectively. Similarly, a 10 μg/m<sup>3</sup> increment in PM<sub>10</sub> was associated with a 0.54 % (0.10 %, 0.98 %) and 1.21 % (0.69 %, 1.72 %) increase in mortality when daily air temperature was set to the 1<sup>st</sup> and 99<sup>th</sup> city-specific percentiles, respectively. Corresponding mortality estimate for O<sub>3</sub> across these temperature percentiles were 0.00 % (-0.44 %, 0.44 %) and 0.53 % (0.38 %, 0.68 %). Similar effect modification results, although slightly weaker, were found for PM<sub>2.5</sub> and NO<sub>2</sub>. Conclusions: Suggestive evidence of effect modification between air temperature and air pollutants on mortality during the warm period was found in a global dataset of 620 cities.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/5b073480-3c56-44d1-aa07-12ee8db275e8
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/53378
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.181 (2023)
dc.subjectAir pollution
dc.subjectAir temperature
dc.subjectEffect modification
dc.subjectEpidemiology
dc.subjectMortality
dc.subjectSDG 11 - Sustainable Cities and Communities
dc.titleJoint effect of heat and air pollution on mortality in 620 cities of 36 countrieseng
dc.typeArticleeng
dc.typeArtículospa
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