Prevention of severe perinatal hemolytic disease with intravenous immunoglobulin in a highly sensitized patient

Andueza, Catalina Villalobos; Balmaceda, Manuel José Monckeberg; González, Cristian Kottman; Rocuant, Juan Carlos Arteaga; Ebensperger, Enrique Oyarzún

Prevention of severe perinatal hemolytic disease with intravenous immunoglobulin in a highly sensitized patient

Authors

Andueza, Catalina Villalobos

Balmaceda, Manuel José Monckeberg

González, Cristian Kottman

Rocuant, Juan Carlos Arteaga

Ebensperger, Enrique Oyarzún

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Description

<p>Perinatal Hemolytic Disease is uncommon today due to its prevention. However, there are cases of highly sensitized mothers who wish to have a child, that forces this desired pregnancy to be controlled in a special way and be subjected to invasive procedures not exempt from fetal morbidity and mortality. Prenatal use of human inmunoglobulin in the mother may represent a therapeutic alternative. We present a case in which its use prevented the development of intrauterine disease and favored a good neonatal evolution despite the fact that the initial prognosis was very adverse.</p>

Keywords

Cordocentesis, Immunoglobulin, Intrauterine transfusion, Perinatal hemolytic disease, Rh(D) isoinmmunization, SDG 3 - Good Health and Well-being

Collections

Clínica UANDES