The oral-gut-circulatory axis: from homeostasis to colon cancer

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dc.coverageDOI: 10.3389/fcimb.2023.1289452
dc.creatorTortora, Sofia C.
dc.creatorGonzález Agurto, María Inés
dc.creatorMartello, Laura A.
dc.date2023
dc.date.accessioned2025-11-18T19:55:30Z
dc.date.available2025-11-18T19:55:30Z
dc.descriptionThe human microbiota is widely recognized as providing crucial health benefits to its host, specifically by modulating immune homeostasis. Microbial imbalance, known as dysbiosis, is linked to several conditions in the body. The oral cavity and gut host the two largest microbial communities playing a major role in microbial-associated diseases. While the oral-gut axis has been previously explored, our review uniquely highlights the significance of incorporating the circulatory system into this axis. The interaction between immune cells, inflammatory factors, circulating bacteria, and microbial metabolites influences the homeostasis of both the oral and gut microbiota in a bidirectional manner. In this comprehensive review, we aim to describe the bacterial components of the oral-gut-circulatory axis in both health and disease, with a specific focus on colon cancer.eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/a9ef97bc-6251-4233-8371-3e8268fc966e
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/59305
dc.languageeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourcevol.13 (2023) date: 2023-11-07 p.1-15
dc.subjectcirculation
dc.subjectcolon cancer
dc.subjectdysbiosis
dc.subjectimmune response
dc.subjectmicrobiota
dc.subjectoral-gut axis
dc.subjectSDG 3 - Good Health and Well-being
dc.titleThe oral-gut-circulatory axis: from homeostasis to colon cancereng
dc.typeArticleeng
dc.typeArtículospa
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