Towards an autonomous system with exhaled breath separation for cleaner condensed air samples
| dc.creator | Carlos Pizarro, F. | |
| dc.creator | Nettle, Cristobal J. | |
| dc.creator | Araneda, Oscar F. | |
| dc.creator | Tuesta, Marcelo | |
| dc.date | 2020 | |
| dc.date.accessioned | 2025-11-18T19:40:06Z | |
| dc.date.available | 2025-11-18T19:40:06Z | |
| dc.description | <p>The acquisition of condensed samples of exhaled air is a well-known noninvasive method for analyzing the healthiness of the lungs. Unlike other invasive methods as induced sputum or bronchoscopy, the condensate collection is faster and non-aggressive. During breathing, it is interesting to fractionate the sample in two differentiated portions as the first exhaled portion comes from a section of the respiratory way known as Dead Space, while the lasting exhaled portion comes from a section known as Alveolar Space. The liquid collected from the Dead Space contains a low-to-none density of biomarkers, which are mainly contained in the Alveolar Space's breathed air. Novel procedures have shown that separating the samples results in a more precise analysis of the state of the patient, improving the collected data for enhancing the current description of associated diseases. Here we describe a novel device and the associated theoretical bases for detecting and separating the exhaled air based on the source area. The implemented system integrates a closed loop for pressure control which operates on a three-ways balloon valve, based on the instantaneous exhaled amount of carbon dioxide following a proven methodology that dynamically fits the expected measured range a patient, providing a reliable cut-off among air spaces. The device, available in an open repository, besides being far less expensive than commercial devices provides a simpler and shorter method for acquiring samples.</p> | eng |
| dc.identifier | https://investigadores.uandes.cl/en/publications/72097e56-ea0c-466a-a017-6ab247a1fd81 | |
| dc.identifier.uri | https://repositorio.uandes.cl/handle/uandes/51115 | |
| dc.language | eng | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.title | Towards an autonomous system with exhaled breath separation for cleaner condensed air samples | eng |
| dc.type | Paper | eng |
| dc.type | Artículo | spa |