Oral squamous cell carcinomas and oral potentially malignant disorders: a Latin American study

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dc.coverageDOI: 10.1111/odi.14778
dc.creatorGilligan, Gerardo
dc.creatorPanico, René
dc.creatorLazos, Jerónimo
dc.creatorMorelatto, Rosana
dc.creatorBelardinelli, Paola
dc.creatorCriscuolo, Ines
dc.creatorBolesina, Nicolas
dc.creatorMolina Ávila, Ignacio
dc.creatorPimentel Solá, Juan Martin
dc.creatorRivarola, Emilce
dc.creatorMorgante, Maria Jimena
dc.creatorIngrassia Tonelli, Maria Eugenia
dc.creatorGimenez, Javier
dc.creatorDoratti, Pablo
dc.creatorWerner, Laura Cecilia
dc.creatorPrado-Ribeiro, Ana Carolina
dc.creatorBrandão, Thais Bianca
dc.creatorVechiato-Filho, Aljomar Jose
dc.creatorCuzzullin, Maria Claudia
dc.creatorSaldivia-Siracusa, Cristina
dc.creatorLopes, Marcio Ajudarte
dc.creatorAgostini, Michelle
dc.creatorRomañach, Mario José
dc.creatorAbrahão, Aline Corrêa
dc.creatorFonsêca, Thamyres Campos
dc.creatorKaminagakura, Estela
dc.creatorAnbinder, Ana Lia
dc.creatorSantos Alves, Kamilla
dc.creatorde Almeida Lança, Maria Leticia
dc.creatorSacsaquispe-Contreras, Sonia
dc.creatorRodriguez Ibazetta, Karem
dc.creatorGerber-Mora, Roberto
dc.creatorAranda Romo, Saray
dc.creatorTejeda Nava, Francisco Javier
dc.creatorCordero-Torres, Karina
dc.creatorMoreno Silva, Ricardo
dc.creatorGonzalez-Arriagada, Wilfredo
dc.creatorToro, Raiza
dc.creatorSilveira, Felipe Martins
dc.creatorGonzalez, Natalia
dc.creatorVargas, Pablo Agustin
dc.creatorSantos-Silva, Alan Roger
dc.creatorBologna-Molina, Ronell
dc.creatorVillarroel-Dorrego, Mariana
dc.creatorMartinez, Benjamin
dc.creatorPiemonte, Eduardo
dc.date2023
dc.date.accessioned2025-11-18T19:49:28Z
dc.date.available2025-11-18T19:49:28Z
dc.description<p>Objective: To determine the frequency of oral squamous cell carcinoma (OSCC) associated or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and traditional risk factors in Latin America. Methods: A retrospective observational study was conducted in 17 Latin American centres. There were included cases of OSCC, analysing age, gender, OSCC and their association with previous OPMD. Clinicopathological variables were retrieved. The condition of sequential-OSCC versus OSCC-de novo (OSCC-dn) was analysed concerning the aforementioned variables. Quantitative variables were analysed using Student's t-test, and qualitative variables with chi-square. Results: In total, 2705 OSCC were included with a mean age of 62.8 years old. 55.8% were men. 53.75% of the patients were smokers and 38% were common drinkers. The lateral tongue border was the most affected site (24.65%). There were regional variations in OPMD, being leukoplakia the most frequent. Of the overall 2705 OSCC cases, 81.4% corresponded to OSCC-dn, while s-OSCC were 18.6%. Regarding lip vermillion SCC, 35.7% corresponded to de novo lip SCC and 64.3% were associated with previous OPMD. Conclusions: In Latin America, OSCC-dn seems to be more frequent with regional variations of some clinical and histopathological features. Further prospective studies are needed to analyse this phenomenon.</p>eng
dc.identifierhttps://investigadores.uandes.cl/en/publications/b98b3b2c-bfdb-4c93-9f17-f8a2e346494d
dc.identifier.urihttps://repositorio.uandes.cl/handle/uandes/56107
dc.languageeng
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourcevol.30 (2023) date: 2023-10-25 nr.5 p.2965-2984
dc.subjectLatin America
dc.subjectleukoplakia
dc.subjectoral cancer
dc.subjectoral potentially malignant disorders
dc.subjectoral squamous cell carcinoma
dc.subjectSDG 3 - Good Health and Well-being
dc.titleOral squamous cell carcinomas and oral potentially malignant disorders: a Latin American studyeng
dc.typeArticleeng
dc.typeArtículospa
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